You may connect to Denodo from R by using the JDBC Driver provided in the Denodo Platform.
The JDBC driver is available in *<DENODO_HOME>/tools/client-drivers/jdbc/vdp-jdbcdriver-core/denodo-vdp-jdbcdriver.jar*
and the class that implements the driver is *com.denodo.vdp.jdbc.Driver*.
You may need to install RJDBC and rJava packages for JDBC connections to work.
You can refer to [Access Through JDBC](https://community.denodo.com/docs/html/browse/7.0/vdp/developer/access_through_jdbc/access_through_jdbc) section of the Virtual DataPort Developer Guide and the similar community question [Connect to Denodo from R](https://community.denodo.com/answers/question/details?questionId=9060g000000XdIKAA0&Connect+to+Denodo+from+R) for more information.
Hope this helps!