Denodo provides several options for the northbound connection. E.g Access through ODBC, JDBC or publish the views as web services. You may need to identify the interface that better suits in your scenario.
You can also write data through Denodo to the underlying source database if the views are "updateable". For more information, you can read the section [Inserts, Updates and Deletes Over Views](https://community.denodo.com/docs/html/browse/7.0/vdp/vql/inserts_updates_and_deletes_over_views/inserts_updates_and_deletes_over_views) in the Virtual DataPort VQL Guide.
Hope this helps!